NOTCH3 (human), recombinant protein

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ABS-PQ-067-L.20	20 µg		-	-	10 - 15 business days*		295.00€
ABS-PQ-067-L.100	100 µg		-	-	10 - 15 business days*		565.00€

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Protein function: Functions as a receptor for membrane-bound ligands Jagged1, Jagged2 and Delta1... more

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Product information "NOTCH3 (human), recombinant protein"

Protein function: Functions as a receptor for membrane-bound ligands Jagged1, Jagged2 and Delta1 to regulate cell-fate determination (PubMed:15350543). Upon ligand activation through the released notch intracellular domain (NICD) it forms a transcriptional activator complex with RBPJ/RBPSUH and activates genes of the enhancer of split locus. Affects the implementation of differentiation, proliferation and apoptotic programs. [The UniProt Consortium]

Keywords:	Neurogenic locus notch homolog protein 3, Notch 3) [Cleaved into: Notch 3 extracellular truncation, Notch 3 intracellular domain], Recombinant Human NOTCH3 Protein
Supplier:	Absea
Supplier-Nr:	PQ-067-L

Properties

Conjugate:	No
Host:	human cells
Species reactivity:	human
MW:	29.5 kD
Format:	Lyophilized

Database Information

KEGG ID :	K20995 \| Matching products
UniProt ID :	Q9UM47 \| Matching products
Gene ID :	GeneID 4854 \| Matching products

Handling & Safety

Storage:	-20°C (protect from light & moisture)
Shipping:	+20°C (International: +20°C)

Caution
Our products are for laboratory research use only: Not for administration to humans!

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