NIP7/KD93 Protein(N-6His) (recombinant human)

Protein Construction: Recombinant Human 60S Ribosome Subunit Biogenesis Protein NIP7 Homolog is produced by our E.coli expression system and the target gene encoding Met1-Thr180 is expressed with a 6His tag at the N-terminus. Sequence: Met 1-Thr180. Fusion tag: N-6His Endotoxin: < 1.0 EU per µg as determined by the LAL method. Apparent Molecular Mass: 20 kDa. Protein function: 60S Ribosome Subunit Biogenesis Protein NIP7 Homolog (NIP7) belongs to the NIP7 family. NIP7 contains one PUA domain, it is essential for the process of proper 27S pre-rRNA and 60S ribosome subunit assembly. NIP7 is a monomer form and interacts with NOL8 and SBDS, and may bind to RNA. In addition, NIP7 is one of the many trans-acting factors required for eukaryotic ribosome biogenesis, which interacts with nascent pre-ribosomal particles and dissociates as they complete maturation and are exported to the cytoplasm. Protein function: Required for proper 34S pre-rRNA processing and 60S ribosome subunit assembly. [The UniProt Consortium]