Neuronal Specific Enolase (NSE)

Protein Length: Ser2- Leu434. Protein Tag: N terminal containing a HIS tag. NSE is the ?? isoform of the glycolytic enzyme enolase and is expressed primarily in neurons, in normal and neoplastic neuroendocrine cells . NSE is a highly soluble cytoplasmic protein that is readily secreted into the CSF and serum following tissue damage. NSE shows neurotrophic and neuroprotective properties on a broad spectrum of central nervous system (CNS) neurons and binds in a calciumdependent manner to cultured neocortical neurons promoting cell survival. RANDOX recombinant NSE comprises a 433 amino acid fragment (2-434) corresponding to processed mature NSE protein and is expressed in E. coli with an amino-terminal hexahistidine tag. This product is for research use only and is not intended for diagnostic or therapeutic use.