Neuronal pentraxin-1 (Nptx1), mouse, recombinant

Organism: Mus musculus (Mouse). Source: E.coli. Expression Region: 23-432aa. Protein Length: Full Length of Mature Protein. Tag Info: N-terminal 6xHis-tagged. Target Protein Sequence: QDFGPTRFIC TSVPVDADMC AASVAAGGAE ELRSNVLQLR ETVLQQKETI LSQKETIREL TTKLGRCESQ STLDSGPGEA RSGGGRKQPG SGKNTMGDLS RTPAAETLSQ LGQTLQSLKT RLENLEQYSR LNSSSQTNSL KDLLQSKIDD LERQVLSRVN TLEEGKGGPK NDTEERAKIE SALTSLHQRI SELEKGQKDN RPGDKFQLTF PLRTNYMYAK VKKSLPEMYA FTVCMWLKSS AAPGVGTPFS YAVPGQANEL VLIEWGNNPM EILINDKVAK LPFVINDGKW HHICVTWTTR DGVWEAYQDG TQGGNGENLA PYHPIKPQGV LVLGQEQDTL GGGFDATQAF VGELAHFNIW DRKLTPGEVY NLATCSSKAL SGNVIAWAES QIEIFGGATK WTFEACRQIN. Purity: Greater than 90% as determined by SDS-PAGE. Endotoxin: Not test. Biological Activity: n/a. Form: Liquid or Lyophilized powder. Buffer: If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0. Reconstitution: We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20 °C/-80 °C. Our default final concentration of glycerol is 50%. Customers could use it as reference. Storage: The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20 °C/-80 °C. The shelf life of lyophilized form is 12 months at -20 °C/-80 °C. Notes: Repeated freezing and thawing is not recommended. Store working aliquots at 4 °C for up to one week. Relevance: May be involved in mediating uptake of synaptic material during synapse remodeling or in mediating the synaptic clustering of AMPA glutamate receptors at a subset of excitatory synapses. Reference: "Biochemical interactions of the neuronal pentraxins. Neuronal pentraxin (NP) receptor binds to taipoxin and taipoxin-associated calcium-binding protein 49 via NP1 and NP2." Kirkpatrick L.L., Matzuk M.M., Dodds D.C., Perin M.S. J. Biol. Chem. 275:17786-17792(2000). Function: nan