Neuroligin 4, X-Linked/NLGN4X Protein(C-6His) (recombinant human)

Protein Construction: Recombinant Human Neuroligin 4, X-Linked is produced by our Mammalian expression system and the target gene encoding Gln42-Ser676 is expressed with a 6His tag at the C-terminus. Sequence: Gln42-Ser676. Fusion tag: C-6His Endotoxin: < 1.0 EU per µg as determined by the LAL method. Apparent Molecular Mass: 95 kDa. Protein function: Neuroligin 4, X-Linked (NLGN4X) is a single-pass type I membrane protein that belongs to the type-B carboxylesterase/lipase family. NLGN4X is detected at higher levels in heart and at lower levels in the liver, skeletal muscle, and pancreas. NLGN4X is a putative neuronal cell surface protein involved in cell-cell-interactions. NLGN4X may act as splice site-specific ligands for ß-neurexins. It has been shown that NLGN4X is involved in the formation and remodeling of central nervous system synapses. NLGN4X also interacts with discs, large (Drosophila) homolog 4 (DLG4). Defects in NLGN4X have been associated with autism and Asperger syndrome. Protein function: Putative neuronal cell surface protein involved in cell- cell-interactions. [The UniProt Consortium]