NCAM Protein (ECD, His Tag) (recombinant human)

Protein Construction: A DNA sequence encoding the human NCAM1 (NP_001070150.1) (Met1-Pro603) was expressed with a polyhistidine tag at the C-terminus. Sequence: Met 1-Pro603. Fusion tag: C-His Endotoxin: < 1.0 EU per µg as determined by the LAL method. Protein function: NCAM1, also known as CD56, is a neural adhesion protein (NCAM) which belongs to the immunoglobulin superfamily. NCAM is involved in neural development and in plasticity in the adult brain. UCHL1 is a novel interaction partner of both NCAM isoforms that regulates their ubiquitination and intracellular trafficking. NCAM1 is a cell adhesion molecule involved in neuron-neuron adhesion, neurite fasciculation, outgrowth of neurites, etc. NCAM1 has also been shown to be involved in the expansion of T cells and dendritic cells which play an important role in immune surveillance. Protein function: This protein is a cell adhesion molecule involved in neuron-neuron adhesion, neurite fasciculation, outgrowth of neurites, etc. [The UniProt Consortium]