Nanog, Recombinant, Human, aa1-305 (Early Embryo Specific Expression NK Family Gene, Embryonic Stem

Nanog, Recombinant, Human, aa1-305 (Early Embryo Specific Expression NK Family Gene, Embryonic Stem
Item number Size Datasheet Manual SDS Delivery time Quantity Price
N0019-01Z.100 100 µg - -

3 - 19 business days*

568.00€
N0019-01Z.500 500 µg - -

3 - 19 business days*

1,099.00€
 
Nanog homeobox, also known as nanog, is a member of the homeobox family of DNA binding... more
Product information "Nanog, Recombinant, Human, aa1-305 (Early Embryo Specific Expression NK Family Gene, Embryonic Stem"
Nanog homeobox, also known as nanog, is a member of the homeobox family of DNA binding transcription factors that has been shown to maintain pluripotency of embryonic stem cells. Nanog expression counteracts the differentiation-promoting signals induced by the extrinsic factors LIF, Stat3 and BMP. Once NANOG expression is downregulated, cell differentiation can proceed. Proteins which regulate NANOG expression include transcription factors Oct4, SOX2, FoxD3, and Tcf3 and tumor suppressor p53. Source: Recombinant corresponding to aa1-305 of human Nanog, expressed in E.coli. AA sequence: MSVDPACPQS LPCFEASDCK ESSPMPVICG PEENYPSLQM SSAEMPHTET VSPLPSSMDL LIQDSPDSST SPKGKQPTSA EKSVAKKEDK VPVKKQKTRT VFSSTQLCVL NDRFQRQKYL SLQQMQELSN ILNLSYKQVK TWFQNQRMKS KRWQKNNWPK NSNGVTQKAS APTYPSLYSS YHQGCLVNPT GNLPMWSNQT WNNSTWSNQT QNIQSWSNHS WNTQTWCTQS WNNQAWNSPF YNCGEESLQS CMQFQPNSPA SDLEAALEAA GEGLNVIQQT TRYFSTPQTM DLFLNYSMNM QPEDV, Molecular Weight: ~34.6kD (305aa), Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 6 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Keywords: hNanog, Homeobox protein NANOG, Homeobox transcription factor Nanog
Supplier: United States Biological
Supplier-Nr: N0019-01Z

Properties

Conjugate: No
MW: 34,6 kD
Format: Highly Purified

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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