Nanodisc Human SCN5A-Strep Protein

Nanodisc Human SCN5A-Strep Protein
Item number Size Datasheet Manual SDS Delivery time Quantity Price
G-HDFP1349.10 10 µg -

9 - 20 business days*

1,605.00€
 
Protein function: This protein mediates the voltage-dependent sodium ion permeability of... more
Product information "Nanodisc Human SCN5A-Strep Protein"
Protein function: This protein mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient (PubMed:1309946, PubMed:21447824, PubMed:25370050, PubMed:23420830, PubMed:23085483, PubMed:26279430, PubMed:26392562, PubMed:26776555). It is a tetrodotoxin-resistant Na(+) channel isoform (PubMed:1309946). This channel is responsible for the initial upstroke of the action potential. Channel inactivation is regulated by intracellular calcium levels (PubMed:19074138). [The UniProt Consortium]
Keywords: hH1, SCN5A, Sodium channel protein type V subunit alpha, Sodium channel protein type 5 subunit alpha, Voltage-gated sodium channel subunit alpha Nav1.5, Sodium channel protein cardiac muscle subunit alpha
Supplier: Assay Genie
Supplier-Nr: HDFP1349

Properties

Conjugate: No
Host: Human cells
Species reactivity: human

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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