Nanodisc Human GPR52 Protein

Nanodisc Human GPR52 Protein
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Item number Size Datasheet Manual SDS Delivery time Quantity Price
G-HDFP303.10 10 µg -

9 - 20 business days*

1,486.00€
 
Protein function: Gs-coupled receptor activated by antipsychotics reserpine leading to an... more
Product information "Nanodisc Human GPR52 Protein"
Protein function: Gs-coupled receptor activated by antipsychotics reserpine leading to an increase in intracellular cAMP and its internalization (PubMed:24587241). May play a role in locomotor activity through modulation of dopamine, NMDA and ADORA2A-induced locomotor activity. These behavioral changes are accompanied by modulation of the dopamine receptor signaling pathway in striatum (PubMed:24587241). Modulates HTT level via cAMP-dependent but PKA independent mechanisms throught activation of RAB39B that translocates HTT to the endoplasmic reticulum, thus avoiding proteasome degradation (PubMed:25738228). [The UniProt Consortium]
Keywords: G-protein coupled receptor 52
Supplier: Assay Genie
Supplier-Nr: HDFP303

Properties

Conjugate: No
Host: Human cells
Species reactivity: human

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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