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| Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
|---|---|---|---|---|---|---|---|
| G-HDFP269.10 | 10 µg | - |
9 - 20 business days* |
1,693.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Protein function: Key negative regulator of Shh signaling, which promotes the processing of GLI3... more
Product information "Nanodisc Human GP161 Protein"
Protein function: Key negative regulator of Shh signaling, which promotes the processing of GLI3 into GLI3R during neural tube development. Recruited by TULP3 and the IFT-A complex to primary cilia and acts as a regulator of the PKA-dependent basal repression machinery in Shh signaling by increasing cAMP levels, leading to promote the PKA-dependent processing of GLI3 into GLI3R and repress the Shh signaling. In presence of SHH, it is removed from primary cilia and is internalized into recycling endosomes, preventing its activity and allowing activation of the Shh signaling. Its ligand is unknown. [The UniProt Consortium]
| Keywords: | GPR161, G-protein coupled receptor 161, G-protein coupled receptor RE2 |
| Supplier: | Assay Genie |
| Supplier-Nr: | HDFP269 |
Properties
| Conjugate: | No |
| Host: | Human cells |
| Species reactivity: | human |
Database Information
| KEGG ID : | K08439 | Matching products |
| UniProt ID : | Q8N6U8 | Matching products |
| Gene ID : | GeneID 23432 | Matching products |
Handling & Safety
| Storage: | -20°C |
| Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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