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NEW
| Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
|---|---|---|---|---|---|---|---|
| G-HDFP1442.10 | 10 µg | - |
9 - 20 business days* |
1,336.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Protein function: Glycine receptors are ligand-gated chloride channels (PubMed:23994010,... more
Product information "Nanodisc Human GLRA1-Strep Protein"
Protein function: Glycine receptors are ligand-gated chloride channels (PubMed:23994010, PubMed:25730860). Channel opening is triggered by extracellular glycine (PubMed:2155780, PubMed:7920629, PubMed:14551753, PubMed:16144831, PubMed:22715885, PubMed:22973015, PubMed:25973519, PubMed:9009272). Channel opening is also triggered by taurine and beta- alanine (PubMed:16144831, PubMed:9009272). Channel characteristics depend on the subunit composition, heteropentameric channels are activated by lower glycine levels and display faster desensitization (PubMed:14551753). Plays an important role in the down-regulation of neuronal excitability (PubMed:8298642, PubMed:9009272). Contributes to the generation of inhibitory postsynaptic currents (PubMed:25445488). Channel activity is potentiated by ethanol (PubMed:25973519). Potentiation of channel activity by intoxicating levels of ethanol contribute to the sedative effects of ethanol. [The UniProt Consortium]
| Keywords: | GLRA1, Glycine receptor 48 kDa subunit, Glycine receptor subunit alpha-1, Glycine receptor strychnine-binding subunit |
| Supplier: | Assay Genie |
| Supplier-Nr: | HDFP1442 |
Properties
| Conjugate: | No |
| Host: | Human cells |
| Species reactivity: | human |
Database Information
| KEGG ID : | K05193 | Matching products |
| UniProt ID : | P23415 | Matching products |
| Gene ID : | GeneID 2741 | Matching products |
Handling & Safety
| Storage: | -20°C |
| Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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