NAE1 (human), recombinant protein

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ABS-PP-5033-L.20	20 µg	-	-	-	Request delivery time estimate		115.00€
ABS-PP-5033-L.100	100 µg	-	-	-	Request delivery time estimate		205.00€

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Protein function: Regulatory subunit of the dimeric UBA3-NAE1 E1 enzyme. E1 activates NEDD8 by... more

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Product information "NAE1 (human), recombinant protein"

Protein function: Regulatory subunit of the dimeric UBA3-NAE1 E1 enzyme. E1 activates NEDD8 by first adenylating its C-terminal glycine residue with ATP, thereafter linking this residue to the side chain of the catalytic cysteine, yielding a NEDD8-UBA3 thioester and free AMP. E1 finally transfers NEDD8 to the catalytic cysteine of UBE2M. Necessary for cell cycle progression through the S-M checkpoint. Overexpression of NAE1 causes apoptosis through deregulation of NEDD8 conjugation. [The UniProt Consortium]

Keywords:	NEDD8-activating enzyme E1 regulatory subunit, Amyloid beta precursor protein-binding protein 1, 59 kDa, APP-BP1, Amyloid protein-binding protein 1, Proto-oncogene protein 1, Recombinant Human NAE1 Protein
Supplier:	Absea
Supplier-Nr:	PP-5033-L

Properties

Conjugate:	No
Host:	E.coli
Species reactivity:	human
MW:	12 kD
Format:	Lyophilized

Database Information

KEGG ID :	K04532 \| Matching products
UniProt ID :	Q13564 \| Matching products
Gene ID :	GeneID 8883 \| Matching products

Handling & Safety

Storage:	-20°C (protect from light & moisture)
Shipping:	+20°C (International: +20°C)

Caution
Our products are for laboratory research use only: Not for administration to humans!

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