MSL2 (human), recombinant protein

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ABS-PP-8703-L.20	20 µg		-	-	Request delivery time estimate		115.00€
ABS-PP-8703-L.100	100 µg		-	-	Request delivery time estimate		205.00€

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Protein function: Component of histone acetyltransferase complex responsible for the majority of... more

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Product information "MSL2 (human), recombinant protein"

Protein function: Component of histone acetyltransferase complex responsible for the majority of histone H4 acetylation at lysine 16 which is implicated in the formation of higher-order chromatin structure. Acts as an E3 ubiquitin ligase that promotes monoubiquitination of histone H2B at 'Lys-35' (H2BK34Ub), but not that of H2A. This activity is greatly enhanced by heterodimerization with MSL1. H2B ubiquitination in turn stimulates histone H3 methylation at 'Lys-4' (H3K4me) and 'Lys-79' (H3K79me) and leads to gene activation, including that of HOXA9 and MEIS1. [The UniProt Consortium]

Keywords:	E3 ubiquitin-protein ligase MSL2, E3 ubiquitin-protein transferase MSL2, Male-specific lethal 2-like 1, MSL2-like 1, Male-specific lethal-2 homolog, MSL-2, Male-specific lethal-2 homolog 1, RING finger protein 184, Recombinant Human MSL2 Protein
Supplier:	Absea
Supplier-Nr:	PP-8703-L

Properties

Conjugate:	No
Host:	E.coli
Species reactivity:	human
MW:	14 kD
Format:	Lyophilized

Database Information

KEGG ID :	K13164 \| Matching products
UniProt ID :	Q9HCI7 \| Matching products
Gene ID :	GeneID 55167 \| Matching products

Handling & Safety

Storage:	-20°C (protect from light & moisture)
Shipping:	+20°C (International: +20°C)

Caution
Our products are for laboratory research use only: Not for administration to humans!

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