MSH3 (human), recombinant protein

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ABS-PP-6302-L.20	20 µg	-	-	-	Request delivery time estimate		115.00€
ABS-PP-6302-L.100	100 µg	-	-	-	Request delivery time estimate		205.00€

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Protein function: Component of the post-replicative DNA mismatch repair system (MMR).... more

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Product information "MSH3 (human), recombinant protein"

Protein function: Component of the post-replicative DNA mismatch repair system (MMR). Heterodimerizes with MSH2 to form MutS beta which binds to DNA mismatches thereby initiating DNA repair. When bound, the MutS beta heterodimer bends the DNA helix and shields approximately 20 base pairs. MutS beta recognizes large insertion-deletion loops (IDL) up to 13 nucleotides long. After mismatch binding, forms a ternary complex with the MutL alpha heterodimer, which is thought to be responsible for directing the downstream MMR events, including strand discrimination, excision, and resynthesis. [The UniProt Consortium]

Keywords:	DNA mismatch repair protein Msh3, hMSH3, Divergent upstream protein, DUP, Mismatch repair protein 1, MRP1, Recombinant Human MSH3 Protein
Supplier:	Absea
Supplier-Nr:	PP-6302-L

Properties

Conjugate:	No
Host:	E.coli
Species reactivity:	human
MW:	14.5 kD
Format:	Lyophilized

Database Information

KEGG ID :	K08736 \| Matching products
UniProt ID :	P20585 \| Matching products
Gene ID :	GeneID 4437 \| Matching products

Handling & Safety

Storage:	-20°C (protect from light & moisture)
Shipping:	+20°C (International: +20°C)

Caution
Our products are for laboratory research use only: Not for administration to humans!

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