Mouse WISP1 Protein

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
KT-WIP-MM101-100UG	100 µg		-		7 - 10 business days*		337.00€
KT-WIP-MM101-500UG	500 µg		-		7 - 10 business days*		1,122.00€

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Recombinant Mouse WISP1 Protein is expressed from HEK293 with His tag at the C-Terminus.It... more

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Product information "Mouse WISP1 Protein"

Recombinant Mouse WISP1 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Thr23-Asn367. The interplay between glioma stem cells (GSCs) and the tumor microenvironment plays crucial roles in promoting malignant growth of glioblastoma (GBM), the most lethal brain tumor. WISP1 is preferentially expressed and secreted by GSCs. Silencing WISP1 markedly disrupts GSC maintenance, reduces tumor-supportive TAMs (M2), and potently inhibits GBM growth. WISP1 signals through Integrin alpha6beta1-Akt to maintain GSCs by an autocrine mechanism and M2 TAMs through a paracrine manner.

Keywords:	ELM-1, WISP-1, CCN4, WISP1c, WISP1i, WISP1tc
Supplier:	KACTUS
Supplier-Nr:	WIP-MM101

Properties

Host:	Human cells
Species reactivity:	mouse
MW:	39.4 kD
Purity:	>95% (Tris-Bis PAGE)
Format:	Lyophilized

Database Information

UniProt ID :	O54775 \| Matching products
Gene ID :	GeneID 22402 \| Matching products

Handling & Safety

Storage:	-80°C (avoid repeat freezing and thawing cycles)
Shipping:	+20°C (International: +20°C)

Caution
Our products are for laboratory research use only: Not for administration to humans!

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