Mouse SEMA7A Protein

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
KT-SEM-MM17A-100UG	100 µg		-		7 - 10 business days*		245.00€
KT-SEM-MM17A-500UG	500 µg		-		7 - 10 business days*		813.00€

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Recombinant Mouse SEMA7A Protein is expressed from HEK293 with His tag at the C-Terminus.It... more

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Product information "Mouse SEMA7A Protein"

Recombinant Mouse SEMA7A Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Gln45-Ala646. Semaphorin7A (Sema7A) plays an important role in the immunoregulation of the brain.Sema7A is upregulated in the epileptic brain and plays a potential role in the regulation of seizure activity in PTZ-kindled epileptic rats, which may be related to neuroinflammation. Sema7A promotes the inflammatory cytokines TNF-alpha and IL-6 as well as the growth of mossy fibers through the ERK pathway, suggesting that Sema7A may promote seizures by increasing neuroinflammation and activating pathological neural circuits. Sema7A plays a critical role in epilepsy and could be a potential therapeutic target for this neurological disorder.

Keywords:	Semaphorin-7A, Semaphorin-K1, Semaphorin-L, Sema L, CD108, CD108MGC126696, CDw108, H-SEMA-K1, H-Sema-L, JMH, MGC126692, Sema7A, SEMAK1, SEMAL
Supplier:	KACTUS
Supplier-Nr:	SEM-MM17A

Properties

Host:	Human cells
Species reactivity:	mouse
MW:	69.5 kD
Purity:	>95% (Tris-Bis PAGE)
Format:	Lyophilized

Database Information

UniProt ID :	Q9QUR8 \| Matching products
Gene ID :	GeneID 20361 \| Matching products

Handling & Safety

Storage:	-80°C (avoid repeat freezing and thawing cycles)
Shipping:	+20°C (International: +20°C)

Caution
Our products are for laboratory research use only: Not for administration to humans!

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