Mouse SEMA4B Protein

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
KT-SEM-MM14B-100UG	100 µg		-		7 - 10 business days*		260.00€
KT-SEM-MM14B-500UG	500 µg		-		7 - 10 business days*		867.00€

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Recombinant Mouse SEMA4B Protein is expressed from HEK293 with His tag at the C-Terminus.It... more

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Product information "Mouse SEMA4B Protein"

Recombinant Mouse SEMA4B Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Leu31-Glu703. Semaphorin 4B (SEMA4B) inhibits the invasion of non-small cell lung cancer (NSCLC) through PI3K-dependent suppression of MMP9 activation. SEMA4B may induce FoxO1 nuclear retention through suppressing PI3K/Akt signaling pathway, which subsequently inhibited cell growth through the direct nuclear target of FoxO1, p21. A role of SEMA4B in suppressing NSCLC growth, besides its role in inhibiting cell metastasis, and highlights SEMA4B as a promising therapeutic target for NSCLC.

Keywords:	Semaphorin-4B, Semaphorin-C, SEMA4B, KIAA1745, SEMAC, MGC131831, SemC
Supplier:	KACTUS
Supplier-Nr:	SEM-MM14B

Properties

Host:	Human cells
Species reactivity:	mouse
MW:	75.7 kD
Purity:	>95% (Tris-Bis PAGE),>95% (HPLC)
Format:	Lyophilized

Database Information

UniProt ID :	Q62179 \| Matching products
Gene ID :	GeneID 20352 \| Matching products

Handling & Safety

Storage:	-80°C (avoid repeat freezing and thawing cycles)
Shipping:	+20°C (International: +20°C)

Caution
Our products are for laboratory research use only: Not for administration to humans!

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