Mouse Glypican 1/GPC1 Protein

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
KT-GPC-MM111-100UG	100 µg		-		7 - 10 business days*		353.00€
KT-GPC-MM111-500UG	500 µg		-		7 - 10 business days*		1,178.00€

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Recombinant Mouse Glypican 1/GPC1 Protein is expressed from HEK293 with His tag at the... more

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Product information "Mouse Glypican 1/GPC1 Protein"

Recombinant Mouse Glypican 1/GPC1 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Asp24-Ser529. CAR-T cells targeting glypican-1 (GPC1)-specific human and murine CAR-T cells generated from our original anti-human/mouse GPC1 antibody showed strong antitumor effects in xenogeneic and syngeneic mouse models, respectively. Importantly, the murine CAR-T cells enhanced endogenous T cell responses against a non-GPC1 tumor antigen through the mechanism of antigen-spreading and showed synergistic antitumor effects with anti-PD-1 antibody without any adverse effects in syngeneic models.

Keywords:	Glypican-1, FLJ38078, GPC1
Supplier:	KACTUS
Supplier-Nr:	GPC-MM111

Properties

Host:	Human cells
Species reactivity:	mouse
MW:	56.8 kD
Purity:	>95% (Tris-Bis PAGE),>95% (HPLC)
Format:	Lyophilized

Database Information

UniProt ID :	Q9QZF2 \| Matching products
Gene ID :	GeneID 14733 \| Matching products

Handling & Safety

Storage:	-80°C (avoid repeat freezing and thawing cycles)
Shipping:	+20°C (International: +20°C)

Caution
Our products are for laboratory research use only: Not for administration to humans!

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