Mouse EFNA3, recombinant (C-Fc)

Recombinant Mouse Ephrin-A3 is produced by our Mammalian expression system and the target gene encoding Gln23-Gly206 is expressed with a human IgG1 Fc tag at the C-terminus. Protein function: Cell surface GPI-bound ligand for Eph receptors, a family of receptor tyrosine kinases which are crucial for migration, repulsion and adhesion during neuronal, vascular and epithelial development. Binds promiscuously Eph receptors residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. [The UniProt Consortium]