Mouse AMIGO2 Protein

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
KT-AMI-MM102-100UG	100 µg		-		7 - 10 business days*		303.00€
KT-AMI-MM102-500UG	500 µg		-		7 - 10 business days*		1,010.00€

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Recombinant Mouse AMIGO2 Protein is expressed from HEK293 with His tag at the C-Terminus.It... more

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Product information "Mouse AMIGO2 Protein"

Recombinant Mouse AMIGO2 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Met39-Thr397. Bromodomain and extraterminal domain inhibitors (BETi) represent promising therapeutic agents for metastatic melanoma, yet their mechanism of action remains unclear. Here we interrogated the transcriptional effects of BETi and identified AMIGO2, a transmembrane molecule, as a BET target gene essential for melanoma cell survival. AMIGO2 is upregulated in melanoma cells and tissues compared to human melanocytes and nevi, and AMIGO2 silencing in melanoma cells induces G1/S arrest followed by apoptosis.

Keywords:	Amphotein-induced protein 2, AMIGO-2, Alivin-1, DEGA, AMIGO2, ALI1, alivin 1
Supplier:	KACTUS
Supplier-Nr:	AMI-MM102

Properties

Host:	Human cells
Species reactivity:	mouse
MW:	41.8 kD
Purity:	>95% (Tris-Bis PAGE),>95% (HPLC)
Format:	Lyophilized

Database Information

UniProt ID :	Q80ZD9 \| Matching products
Gene ID :	GeneID 105827 \| Matching products

Handling & Safety

Storage:	-80°C (avoid repeat freezing and thawing cycles)
Shipping:	+20°C (International: +20°C)

Caution
Our products are for laboratory research use only: Not for administration to humans!

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