MORC3 (human), recombinant protein

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ABS-PP-471.20	20 µg		-	-	Request delivery time estimate		90.00€
ABS-PP-471.100	100 µg		-	-	Request delivery time estimate		180.00€

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Protein function: Nuclear factor which forms MORC3-NBs (nuclear bodies) via an ATP-dependent... more

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Product information "MORC3 (human), recombinant protein"

Protein function: Nuclear factor which forms MORC3-NBs (nuclear bodies) via an ATP-dependent mechanism (PubMed:20501696). Sumoylated MORC3-NBs can also associate with PML-NBs (PubMed:20501696). Recruits TP53 and SP100 to PML-NBs, thus regulating TP53 activity (PubMed:17332504). Binds RNA in vitro (PubMed:11927593). May be required for influenza A transcription during viral infection (PubMed:26202233). Histone methylation reader which binds to non-methylated (H3K4me0), monomethylated (H3K4me1), dimethylated (H3K4me2) and trimethylated (H3K4me3) 'Lys-4' on histone H3 (PubMed:26933034). The order of binding preference is H3K4me3 > H3K4me2 > H3K4me1 > H3K4me0 (PubMed:26933034). [The UniProt Consortium]

Keywords:	MORC family CW-type zinc finger protein 3, Nuclear matrix protein 2, Zinc finger CW-type coiled-coil domain protein 3, Recombinant Human MORC3 Protein
Supplier:	Absea
Supplier-Nr:	PP-471

Properties

Conjugate:	No
Host:	E.coli
Species reactivity:	human
MW:	108 kD
Format:	Solution

Database Information

KEGG ID :	K24135 \| Matching products
UniProt ID :	Q14149 \| Matching products
Gene ID :	GeneID 23515 \| Matching products

Handling & Safety

Storage:	-20°C (avoid repeat freezing and thawing cycles)
Shipping:	-20°C (International: -20°C)

Caution
Our products are for laboratory research use only: Not for administration to humans!

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