MICU2 (human), recombinant protein

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ABS-PP-8562-L.20	20 µg	-	-	-	10 - 15 business days*		115.00€
ABS-PP-8562-L.100	100 µg	-	-	-	10 - 15 business days*		205.00€

If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk

Protein function: Key regulator of mitochondrial calcium uniporter (MCU) required to limit... more

Close menu

Product information "MICU2 (human), recombinant protein"

Protein function: Key regulator of mitochondrial calcium uniporter (MCU) required to limit calcium uptake by MCU when cytoplasmic calcium is low (PubMed:24503055, PubMed:24560927, PubMed:26903221). MICU1 and MICU2 form a disulfide-linked heterodimer that stimulate and inhibit MCU activity, depending on the concentration of calcium (PubMed:24560927). MICU2 acts as a gatekeeper of MCU that senses calcium level via its EF- hand domains: prevents channel opening at resting calcium, avoiding energy dissipation and cell-death triggering (PubMed:24560927). [The UniProt Consortium]

Keywords:	Calcium uptake protein 2, mitochondrial, EF-hand domain-containing family member A1, Recombinant Human MICU2 Protein
Supplier:	Absea
Supplier-Nr:	PP-8562-L

Properties

Conjugate:	No
Host:	E.coli
Species reactivity:	human
MW:	44 kD
Format:	Lyophilized

Database Information

KEGG ID :	K22828 \| Matching products
UniProt ID :	Q8IYU8 \| Matching products
Gene ID :	GeneID 221154 \| Matching products

Handling & Safety

Storage:	-20°C (protect from light & moisture)
Shipping:	+20°C (International: +20°C)

Caution
Our products are for laboratory research use only: Not for administration to humans!

Information about the product reference will follow. more

Close menu

You will get a certificate here

Go back

Read, write and discuss reviews... more

Close menu

Customer review for "MICU2 (human), recombinant protein"

Write a review