Methyltransferase-like protein 17, mitochondrial (METTL17), recombinant human

Organism: Homo sapiens (Human). Source: Mammalian cell. Expression Region: 20-456aa. Protein Length: Full Length of Mature Protein. Tag Info: C-terminal 10xHis-tagged. Target Protein Sequence: VAPQARALAA LVPGVTQVDN KSGFLQKRPH RQHPGILKLP HVRLPQALAN GAQLLLLGSA GPTMENQVQT LTSYLWSRHL PVEPEELQRR ARHLEKKFLE NPDLSQTEEK LRGAVLHALR KTTYHWQELS YTEGLSLVYM AARLDGGFAA VSRAFHEIRA RNPAFQPQTL MDFGSGTGSV TWAAHSIWGQ SLREYMCVDR SAAMLVLAEK LLKGGSESGE PYIPGVFFRQ FLPVSPKVQF DVVVSAFSLS ELPSKADRTE VVQTLWRKTG HFLVLVENGT KAGHSLLMDA RDLVLKGKEK SPLDPRPGFV FAPCPHELPC PQLTNLACSF SQAYHPIPFS WNKKPKEEKF SMVILARGSP EEAHRWPRIT QPVLKRPRHV HCHLCCPDGH MQHAVLTARR HGRDLYRCAR VSSWGDLLPV LTPSAFPPST AQDPSES. Purity: Greater than 85% as determined by SDS-PAGE. Endotoxin: Not test. Biological Activity: n/a. Form: Liquid or Lyophilized powder. Buffer: If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0. Reconstitution: We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20°C/-80°C. Our default final concentration of glycerol is 50%. Customers could use it as reference. Storage: The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C. Notes: Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week. Relevance: Deubiquitinating enzyme (DUB) that controls levels of cellular ubiquitin through processing of ubiquitin precursors and ubiquitinated proteins. Thiol protease that recognizes and hydrolyzes a peptide bond at the C-terminal glycine of either ubiquitin or RUB1. Preferentially cleaves ubiquitin from peptides and small adducts. Reference: n/a. Function: nan