MEOX1 PrEST Antigen

MEOX1 PrEST Antigen
Item number Size Datasheet Manual SDS Delivery time Quantity Price
ATA-APrEST94874.100 100 µl - -

3 - 8 business days*

264.00€
 
Protein function: Mesodermal transcription factor that plays a key role in somitogenesis and is... more
Product information "MEOX1 PrEST Antigen"
Protein function: Mesodermal transcription factor that plays a key role in somitogenesis and is specifically required for sclerotome development. Required for maintenance of the sclerotome polarity and formation of the cranio-cervical joints (PubMed:23290072, PubMed:24073994). Binds specifically to the promoter of target genes and regulates their expression. Activates expression of NKX3-2 in the sclerotome. Activates expression of CDKN1A and CDKN2A in endothelial cells, acting as a regulator of vascular cell proliferation. While it activates CDKN1A in a DNA-dependent manner, it activates CDKN2A in a DNA-independent manner. Required for hematopoietic stem cell (HSCs) induction via its role in somitogenesis: specification of HSCs occurs via the deployment of a specific endothelial precursor population, which arises within a sub-compartment of the somite named endotome. [The UniProt Consortium] Buffer: PBS and 1M Urea, pH 7.4.
Keywords: MOX1, MEOX1, Mesenchyme homeobox 1, Homeobox protein MOX-1
Supplier: Atlas Antibodies
Supplier-Nr: APrEST94874

Properties

Application: Control antigen
Conjugate: No
Host: E.coli
Species reactivity: human

Handling & Safety

Storage: -20°C (avoid repeat freezing and thawing cycles)
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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