MDL-1/CLEC5A hFc Chimera, Human

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
GSC-Z05642-100	100 µg		-		Request delivery time estimate		497.00€
GSC-Z05642-500	500 µg		-		Request delivery time estimate		1,680.00€

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In C. elegans, increased lifespan in daf-2 insulin/IGF-1 receptor mutants is accompanied by... more

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Product information "MDL-1/CLEC5A hFc Chimera, Human"

In C. elegans, increased lifespan in daf-2 insulin/IGF-1 receptor mutants is accompanied by up-regulation of the MDL-1 Mad basic helix-loop-helix leucine zipper transcription factor.MDL-1, like its mammalian orthologs, is an inhibitor of cell proliferation and growth that slows progression of an age-related pathology in C. elegans (uterine tumors). In addition, intestine-limited rescue of mdl-1 increased lifespan but not to wild type levels. Thus, mdl-1 likely acts both in the intestine and the germline to influence age-related mortality.

Keywords:	CLEC5A, C-type lectin superfamily member 5, Myeloid DAP12-associating lectin 1, C-type lectin domain family 5 member A
Supplier:	GenScript
Supplier-Nr:	Z05642

Properties

Conjugate:	No
Species reactivity:	human
MW:	46 kD
Purity:	>95% (Bis-Tris PAGE)

Database Information

KEGG ID :	K10073 \| Matching products
UniProt ID :	Q9NY25 \| Matching products
Gene ID :	GeneID 23601 \| Matching products

Handling & Safety

Storage:	-20°C
Shipping:	+4°C (International: °C)

Caution
Our products are for laboratory research use only: Not for administration to humans!

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