MCM3AP (human), recombinant protein

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ABS-PP-6344.20	20 µg	-	-	-	Request delivery time estimate		90.00€
ABS-PP-6344.100	100 µg	-	-	-	Request delivery time estimate		180.00€

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Protein function: [Isoform GANP]: As a component of the TREX-2 complex, involved in the export of... more

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Product information "MCM3AP (human), recombinant protein"

Protein function: [Isoform GANP]: As a component of the TREX-2 complex, involved in the export of mRNAs to the cytoplasm through the nuclear pores (PubMed:20005110, PubMed:20384790, PubMed:23591820, PubMed:22307388). Through the acetylation of histones, affects the assembly of nucleosomes at immunoglobulin variable region genes and promotes the recruitment and positioning of transcription complex to favor DNA cytosine deaminase AICDA/AID targeting, hence promoting somatic hypermutations (PubMed:23652018). [The UniProt Consortium]

Keywords:	Germinal-center associated nuclear protein, GANP, 80 kDa MCM3-associated protein, MCM3 acetylating protein, MCM3AP, MCM3 acetyltransferase, Recombinant Human MCM3AP Protein
Supplier:	Absea
Supplier-Nr:	PP-6344

Properties

Conjugate:	No
Host:	E.coli
Species reactivity:	human
MW:	40.5 kD
Format:	Solution

Database Information

KEGG ID :	K24317 \| Matching products
UniProt ID :	O60318 \| Matching products
Gene ID :	GeneID 8888 \| Matching products

Handling & Safety

Storage:	-20°C (avoid repeat freezing and thawing cycles)
Shipping:	-20°C (International: -20°C)

Caution
Our products are for laboratory research use only: Not for administration to humans!

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