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Product information "MCF2L (human), recombinant protein"
Protein function: Guanine nucleotide exchange factor that catalyzes guanine nucleotide exchange on RHOA and CDC42, and thereby contributes to the regulation of RHOA and CDC42 signaling pathways. Seems to lack activity with RAC1. Becomes activated and highly tumorigenic by truncation of the N-terminus. Isoform 5 activates CDC42 (PubMed:15157669). [The UniProt Consortium]
Keywords:
Guanine nucleotide exchange factor DBS, DBL's big sister, MCF2-transforming sequence-like protein, Recombinant Human MCF2L Protein
This website uses cookies, which are necessary for the technical operation of the website and are always set. Other cookies, which increase the usability of this website, serve for direct advertising or simplify interaction with other websites and social networks, will only be used with your consent.
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