MARK3 (human), recombinant protein

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ABS-PP-5806-L.20	20 µg		-	-	Request delivery time estimate		115.00€
ABS-PP-5806-L.100	100 µg		-	-	Request delivery time estimate		205.00€

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Protein function: Serine/threonine-protein kinase (PubMed:23666762). Involved in the specific... more

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Product information "MARK3 (human), recombinant protein"

Protein function: Serine/threonine-protein kinase (PubMed:23666762). Involved in the specific phosphorylation of microtubule-associated proteins for MAP2 and MAP4. Phosphorylates the microtubule-associated protein MAPT/TAU (PubMed:23666762). Phosphorylates CDC25C on 'Ser-216'. Regulates localization and activity of some histone deacetylases by mediating phosphorylation of HDAC7, promoting subsequent interaction between HDAC7 and 14-3-3 and export from the nucleus (PubMed:16980613). Negatively regulates the Hippo signaling pathway and antagonizes the phosphorylation of LATS1. Cooperates with DLG5 to inhibit the kinase activity of STK3/MST2 toward LATS1 (PubMed:28087714). [The UniProt Consortium]

Keywords:	MAP/microtubule affinity-regulating kinase 3, C-TAK1, cTAK1, Cdc25C-associated protein kinase 1, ELKL motif kinase 2, EMK-2, Protein kinase STK10, Ser/Thr protein kinase PAR-1, Par-1a, Serine/threonine-protein kinase p78, Recombinant Human MARK3 Protein
Supplier:	Absea
Supplier-Nr:	PP-5806-L

Properties

Conjugate:	No
Host:	E.coli
Species reactivity:	human
MW:	40 kD
Format:	Lyophilized

Database Information

KEGG ID :	K08798 \| Matching products
UniProt ID :	P27448 \| Matching products
Gene ID :	GeneID 4140 \| Matching products

Handling & Safety

Storage:	-20°C (protect from light & moisture)
Shipping:	+20°C (International: +20°C)

Caution
Our products are for laboratory research use only: Not for administration to humans!

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