Maltase-glucoamylase, intestinal (MGAM), partial, recombinant human

Organism: Homo sapiens (Human). Source: E.coli. Expression Region: 87-954aa. Protein Length: Partial. Tag Info: C-terminal 6xHis-tagged. Target Protein Sequence: SAECPVVNEL ERINCIPDQP PTKATCDQRG CCWNPQGAVS VPWCYYSKNH SYHVEGNLVN TNAGFTARLK NLPSSPVFGS NVDNVLLTAE YQTSNRFHFK LTDQTNNRFE VPHEHVQSFS GNAAASLTYQ VEISRQPFSI KVTRRSNNRV LFDSSIGPLL FADQFLQLST RLPSTNVYGL GEHVHQQYRH DMNWKTWPIF NRDTTPNGNG TNLYGAQTFF LCLEDASGLS FGVFLMNSNA MEVVLQPAPA ITYRTIGGIL DFYVFLGNTP EQVVQEYLEL IGRPALPSYW ALGFHLSRYE YGTLDNMREV VERNRAAQLP YDVQHADIDY MDERRDFTYD SVDFKGFPEF VNELHNNGQK LVIIVDPAIS NNSSSSKPYG PYDRGSDMKI WVNSSDGVTP LIGEVWPGQT VFPDYTNPNC AVWWTKEFEL FHNQVEFDGI WIDMNEVSNF VDGSVSGCST NNLNNPPFTP RILDGYLFCK TLCMDAVQHW GKQYDIHNLY GYSMAVATAE AAKTVFPNKR SFILTRSTFA GSGKFAAHWL GDNTATWDDL RWSIPGVLEF NLFGIPMVGP DICGFALDTP EELCRRWMQL GAFYPFSRNH NGQGYKDQDP ASFGADSLLL NSSRHYLNIR YTLLPYLYTL FFRAHSRGDT VARPLLHEFY EDNSTWDVHQ QFLWGPGLLI TPVLDEGAEK VMAYVPDAVW YDYETGSQVR WRKQKVEMEL PGDKIGLHLR GGYIFPTQQP NTTTLASRKN PLGLIIALDE NKEAKGELFW DNGETKDTVA NKVYLLCEFS VTQNRLEVNI SQSTYKDPNN LAFNEIKILG TEEPSNVTVK HNGVPSQTSP TVTYDSNLKV AIITDIDLLL GEAYTVEW. Purity: Greater than 85% as determined by SDS-PAGE. Endotoxin: Not test. Biological Activity: n/a. Form: Liquid or Lyophilized powder. Buffer: If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0. Reconstitution: We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20°C/-80°C. Our default final concentration of glycerol is 50%. Customers could use it as reference. Storage: The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C. Notes: Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week. Relevance: The H2 subclass of histamine receptors mediates gastric acid secretion. Also appears to regulate gastrointestinal motility and intestinal secretion. Possible role in regulating cell growth and differentiation. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase and, through a separate G protein-dependent mechanism, the phosphoinositide/protein kinase (PKC) signaling pathway. Reference: "Human-specific amino acid changes found in 103 protein-coding genes." Kitano T., Liu Y.-H., Ueda S., Saitou N. Mol. Biol. Evol. 21:936-944(2004). Function: nan