MAD1L1 (human), recombinant protein

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ABS-PP-650.20	20 µg		-	-	Request delivery time estimate		90.00€
ABS-PP-650.100	100 µg		-	-	Request delivery time estimate		180.00€

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Protein function: Component of the spindle-assembly checkpoint that prevents the onset of... more

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Product information "MAD1L1 (human), recombinant protein"

Protein function: Component of the spindle-assembly checkpoint that prevents the onset of anaphase until all chromosomes are properly aligned at the metaphase plate (PubMed:10049595, PubMed:20133940, PubMed:29162720). Forms a heterotetrameric complex with the closed conformation form of MAD2L1 (C-MAD2) at unattached kinetochores during prometaphase, recruits an open conformation of MAD2L1 (O-MAD2) and promotes the conversion of O-MAD2 to C-MAD2, which ensures mitotic checkpoint signaling (PubMed:29162720). [The UniProt Consortium]

Keywords:	Mitotic spindle assembly checkpoint protein MAD1, Mitotic arrest deficient 1-like protein 1, MAD1-like protein 1, Mitotic checkpoint MAD1 protein homolog, HsMAD1, hMAD1, Tax-binding protein 181, Recombinant Human MAD1L1 Protein
Supplier:	Absea
Supplier-Nr:	PP-650

Properties

Conjugate:	No
Host:	E.coli
Species reactivity:	human
MW:	42 kD
Format:	Solution

Database Information

KEGG ID :	K06679 \| Matching products
UniProt ID :	Q9Y6D9 \| Matching products
Gene ID :	GeneID 8379 \| Matching products

Handling & Safety

Storage:	-20°C (avoid repeat freezing and thawing cycles)
Shipping:	-20°C (International: -20°C)

Caution
Our products are for laboratory research use only: Not for administration to humans!

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