LRWD1 (human), recombinant protein

LRWD1 (human), recombinant protein
Item number Size Datasheet Manual SDS Delivery time Quantity Price
ABS-PP-8905.20 20 µg - - -

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90.00€
ABS-PP-8905.100 100 µg - - -

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180.00€
 
Protein function: Required for G1/S transition. Recruits and stabilizes the origin recognition... more
Product information "LRWD1 (human), recombinant protein"
Protein function: Required for G1/S transition. Recruits and stabilizes the origin recognition complex (ORC) onto chromatin during G1 to establish pre-replication complex (preRC) and to heterochromatic sites in post- replicated cells. Binds a combination of DNA and histone methylation repressive marks on heterochromatin. Binds histone H3 and H4 trimethylation marks H3K9me3, H3K27me3 and H4K20me3 in a cooperative manner with DNA methylation. Required for silencing of major satellite repeats. May be important ORC2, ORC3 and ORC4 stability. [The UniProt Consortium]
Keywords: Leucine-rich repeat and WD repeat-containing protein 1, Centromere protein 33, CENP-33, Origin recognition complex-associated protein, ORC-associated protein, ORCA, Recombinant Human LRWD1 Protein
Supplier: Absea
Supplier-Nr: PP-8905

Properties

Conjugate: No
Host: E.coli
Species reactivity: human
MW: 17 kD
Format: Solution

Handling & Safety

Storage: -20°C (avoid repeat freezing and thawing cycles)
Shipping: -20°C (International: -20°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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