LRP-6 Protein, Human, Recombinant (mFc)

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
TGM-TMPK-00744-100ug	100 µg		-		7 - 10 business days*		350.00€
TGM-TMPK-00744-500ug	500 µg		-		7 - 10 business days*		1,412.00€

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Description: Dickkopf-related protein 1 (DKK-1), a ligand for the WNT coreceptors low-density... more

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Product information "LRP-6 Protein, Human, Recombinant (mFc)"

Description: Dickkopf-related protein 1 (DKK-1), a ligand for the WNT coreceptors low-density lipoprotein receptor-related proteins 5 and 6 (LRP-5 and LRP-6) and an inhibitor of WNT/beta-catenin signaling, effectively inhibits pericyte activation, detachment, and transition to myofibroblasts in vivo in response to kidney injury, resulting in attenuated fibrogenesis, capillary rarefaction, and inflammation.LRP-6 interacts closely with PDGF receptor beta and TGF-beta receptor 1 at the cell membrane, suggesting that it may have roles in pathways other than WNT/beta-catenin.

Keywords:	DCAD2, LRP-6, FLJ90421, FLJ90062, LRP6
Supplier:	TargetMol
Supplier-Nr:	TMPK-00744

Properties

Conjugate:	No
MW:	95.3 kD

Database Information

KEGG ID :	K03068 \| Matching products
UniProt ID :	O75581 \| Matching products
Gene ID :	GeneID 4040 \| Matching products

Handling & Safety

Storage:	-20°C
Shipping:	+20°C (International: +4°C)

Caution
Our products are for laboratory research use only: Not for administration to humans!

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