Low-Density Lipoprotein Receptor Related Protein 12/LRP12 Protein(C-6His) (recombinant human)

Protein Construction: Recombinant Human Low-Density Lipoprotein Receptor-Related Protein 12 is produced by our Mammalian expression system and the target gene encoding Asn28-Ile488 is expressed with a 6His tag at the C-terminus. Sequence: Asn28-Ile488. Fusion tag: C-6His Endotoxin: < 1.0 EU per µg as determined by the LAL method. Apparent Molecular Mass: 68 kDa. Protein function: Low-Density Lipoprotein Receptor-Related Protein 12 (LRP12) belongs to the LDLR family. LRP12 is a type I transmembrane protein annd widely expressed in heart, skeletal muscle, brain, lung, placenta and pancreas. LRP12 contains 2 CUB domain and 5 LDL-receptor class A domain. LRP12 has been shown to interact with GNB2L1, ZFYVE9 and ITGB1BP3. LRP12 is a receptor probably, which may be involved in the internalization of lipophilic molecules and/or signal transduction. In addition, LRP12 may act as a tumor suppressor. Protein function: Probable receptor, which may be involved in the internalization of lipophilic molecules and/or signal transduction. May act as a tumor suppressor. [The UniProt Consortium]