LITAF PrEST Antigen

LITAF PrEST Antigen
Item number Size Datasheet Manual SDS Delivery time Quantity Price
ATA-APrEST71014.100 100 µl - -

7 - 10 business days*

264.00€
 
Protein function: Plays a role in endosomal protein trafficking and in targeting proteins for... more
Product information "LITAF PrEST Antigen"
Protein function: Plays a role in endosomal protein trafficking and in targeting proteins for lysosomal degradation (PubMed:23166352). Plays a role in targeting endocytosed EGFR and ERGG3 for lysosomal degradation, and thereby helps downregulate downstream signaling cascades (PubMed:23166352). Helps recruit the ESCRT complex components TSG101, HGS and STAM to cytoplasmic membranes (PubMed:23166352). Probably plays a role in regulating protein degradation via its interaction with NEDD4 (PubMed:15776429). May also contribute to the regulation of gene expression in the nucleus (PubMed:10200294, PubMed:15793005). Binds DNA (in vitro) and may play a synergistic role with STAT6 in the nucleus in regulating the expression of various cytokines (PubMed:15793005). May regulate the expression of numerous cytokines, such as TNF, CCL2, CCL5, CXCL1, IL1A and IL10 (PubMed:10200294, PubMed:15793005). [The UniProt Consortium] Buffer: PBS and 1M Urea, pH 7.4.
Keywords: LITAF, p53-induced gene 7 protein, LPS-induced TNF-alpha factor, Small integral membrane protein of lysosome/late endosome, Lipopolysaccharide-induced tumor necrosis factor-alpha factor
Supplier: Atlas Antibodies
Supplier-Nr: APrEST71014

Properties

Application: Control antigen
Conjugate: No
Host: E.coli
Species reactivity: human

Handling & Safety

Storage: -20°C (avoid repeat freezing and thawing cycles)
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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