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| Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
|---|---|---|---|---|---|---|---|
| G-RPES6629.10 | 10 µg | - | - | - |
9 - 20 business days* |
113.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Protein function: Inhibitory receptor involved in the down-regulation of the immune response... more
Product information "Leukocyte Ig-Like Receptor B4/LILRB4/CD85k/ILT3 (C-Fc) (recombinant mouse)"
Protein function: Inhibitory receptor involved in the down-regulation of the immune response (PubMed:10026201, PubMed:24935931). Receptor for FN1 (PubMed:34089617). Receptor for integrin ITGAV/ITGB3 (PubMed:11323698). Inhibits IgE-mediated mast cell activation, at least in part through interaction with ITGAV/ITGB3 (PubMed:10026201, PubMed:11323698, PubMed:11457897, PubMed:8855262). Also inhibits KITLG/SCF-mediated mast cell activation (PubMed:12884301). Through interaction with ITGAV/ITGB3, inhibits antibody production by memory and marginal zone B cells, probably by suppressing their differentiation into plasma cells (PubMed:24935931). Inhibits IFNG production by CD8 T cells, CD4 T cells and natural killer cells (PubMed:12682239). Inhibits antigen presentation by dendritic cells to T cells, preventing T cell activation (PubMed:18792399). Inhibits lipopolysaccharide-mediated neutrophil-dependent vascular injury (PubMed:14557414). Suppresses the allergic inflammatory response by inhibiting infiltration of neutrophils and eosinophils and preventing mast cell degranulation (PubMed:17761953). Inhibits lysis by natural killer cells (PubMed:8977169). [The UniProt Consortium]
| Keywords: | CD85k, Mast cell surface glycoprotein Gp49B, Leukocyte immunoglobulin-like receptor subfamily B member 4A |
| Supplier: | Assay Genie |
| Supplier-Nr: | RPES6629 |
Properties
| Conjugate: | No |
| Host: | Human cells |
| Species reactivity: | mouse |
| Format: | Lyophilized |
Database Information
| KEGG ID : | K06512 | Matching products |
| UniProt ID : | Q64281 | Matching products |
| Gene ID : | GeneID 14728 | Matching products |
Handling & Safety
| Storage: | -20°C |
| Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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