LDLRAD4 PrEST Antigen

LDLRAD4 PrEST Antigen
Item number Size Datasheet Manual SDS Delivery time Quantity Price
ATA-APrEST88129.100 100 µl - -

7 - 10 business days*

264.00€
 
Protein function: Functions as a negative regulator of TGF-beta signaling and thereby probably... more
Product information "LDLRAD4 PrEST Antigen"
Protein function: Functions as a negative regulator of TGF-beta signaling and thereby probably plays a role in cell proliferation, differentiation, apoptosis, motility, extracellular matrix production and immunosuppression. In the canonical TGF-beta pathway, ZFYVE9/SARA recruits the intracellular signal transducer and transcriptional modulators SMAD2 and SMAD3 to the TGF-beta receptor. Phosphorylated by the receptor, SMAD2 and SMAD3 then form a heteromeric complex with SMAD4 that translocates to the nucleus to regulate transcription. Through interaction with SMAD2 and SMAD3, LDLRAD4 may compete with ZFYVE9 and SMAD4 and prevent propagation of the intracellular signal. [The UniProt Consortium] Buffer: PBS and 1M Urea, pH 7.4.
Keywords: LDLRAD4, C18orf1, Low-density lipoprotein receptor class A domain-containing protein 4
Supplier: Atlas Antibodies
Supplier-Nr: APrEST88129

Properties

Application: Control antigen
Conjugate: No
Host: E.coli
Species reactivity: human

Database Information

UniProt ID : O15165 | Matching products
Gene ID : GeneID 753 | Matching products

Handling & Safety

Storage: -20°C (avoid repeat freezing and thawing cycles)
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
You will get a certificate here
or to request a certificate of analysis.
Read, write and discuss reviews... more
Customer review for "LDLRAD4 PrEST Antigen"
Write a review
or to review a product.
Viewed