LAIR1/CD305 hFc Chimera, Human

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
GSC-Z05558-100	100 µg		-		Request delivery time estimate		524.00€
GSC-Z05558-500	500 µg		-		Request delivery time estimate		1,761.00€

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LAIR1 (leukocyte-associated Ig-like receptor-1, designated CD305) is an approximately 40 kDa type... more

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Product information "LAIR1/CD305 hFc Chimera, Human"

LAIR1 (leukocyte-associated Ig-like receptor-1, designated CD305) is an approximately 40 kDa type I transmembrane inhibitory glycoprotein belonging to the Ig superfamily.LAIR1 functions as an inhibitory receptor that plays a constitutive negative regulatory role on cytolytic function of natural killer (NK) cells, B-cells and T-cells. Activation by Tyr phosphorylation results in recruitment and activation of the phosphatases PTPN6 and PTPN11. It also reduces the increase of intracellular calcium evoked by B-cell receptor ligation.

Keywords:	LAIR1, Leukocyte-associated immunoglobulin-like receptor 1
Supplier:	GenScript
Supplier-Nr:	Z05558

Properties

Conjugate:	No
Species reactivity:	human
MW:	42.4 kD
Purity:	>95% (Bis-Tris PAGE)

Database Information

KEGG ID :	K06725 \| Matching products
UniProt ID :	Q6GTX8 \| Matching products
Gene ID :	GeneID 3903 \| Matching products

Handling & Safety

Storage:	-20°C
Shipping:	+4°C (International: °C)

Caution
Our products are for laboratory research use only: Not for administration to humans!

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