L3MBTL1 PrEST Antigen

L3MBTL1 PrEST Antigen
Item number Size Datasheet Manual SDS Delivery time Quantity Price
ATA-APrEST94300.100 100 µl - -

3 - 8 business days*

264.00€
 
Protein function: Polycomb group (PcG) protein that specifically recognizes and binds mono- and... more
Product information "L3MBTL1 PrEST Antigen"
Protein function: Polycomb group (PcG) protein that specifically recognizes and binds mono- and dimethyllysine residues on target proteins, therey acting as a 'reader' of a network of post-translational modifications. PcG proteins maintain the transcriptionally repressive state of genes: acts as a chromatin compaction factor by recognizing and binding mono- and dimethylated histone H1b/H1-4 at 'Lys-26' (H1bK26me1 and H1bK26me2) and histone H4 at 'Lys-20' (H4K20me1 and H4K20me2), leading to condense chromatin and repress transcription. Recognizes and binds p53/TP53 monomethylated at 'Lys-382', leading to repress p53/TP53- target genes. Also recognizes and binds RB1/RB monomethylated at 'Lys- 860'. Participates in the ETV6-mediated repression. Probably plays a role in cell proliferation. Overexpression induces multinucleated cells, suggesting that it is required to accomplish normal mitosis. [The UniProt Consortium] Buffer: PBS and 1M Urea, pH 7.4.
Keywords: L3MBTL1, KIAA0681, H-l(3)mbt, L(3)mbt-like, H-l(3)mbt protein, L(3)mbt protein homolog, Lethal(3)malignant brain tumor-like protein 1
Supplier: Atlas Antibodies
Supplier-Nr: APrEST94300

Properties

Application: Control antigen
Conjugate: No
Host: E.coli
Species reactivity: human

Handling & Safety

Storage: -20°C (avoid repeat freezing and thawing cycles)
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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