KSR1 (human), recombinant protein

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ABS-PP-5205-L.20	20 µg		-	-	Request delivery time estimate		115.00€
ABS-PP-5205-L.100	100 µg		-	-	Request delivery time estimate		205.00€

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Protein function: Part of a multiprotein signaling complex which promotes phosphorylation of Raf... more

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Product information "KSR1 (human), recombinant protein"

Protein function: Part of a multiprotein signaling complex which promotes phosphorylation of Raf family members and activation of downstream MAP kinases. Independently of its kinase activity, acts as MAP2K1/MEK1 and MAP2K2/MEK2-dependent allosteric activator of BRAF, upon binding to MAP2K1/MEK1 or MAP2K2/MEK2, dimerizes with BRAF and promotes BRAF-mediated phosphorylation of MAP2K1/MEK1 and/or MAP2K2/MEK2 (PubMed:29433126). Promotes activation of MAPK1 and/or MAPK3, both in response to EGF and to cAMP. Its kinase activity is unsure. Some protein kinase activity has been detected in vitro, however the physiological relevance of this activity is unknown. [The UniProt Consortium]

Keywords:	Kinase suppressor of Ras 1, Recombinant Human KSR1 Protein
Supplier:	Absea
Supplier-Nr:	PP-5205-L

Properties

Conjugate:	No
Host:	E.coli
Species reactivity:	human
MW:	13.5 kD
Format:	Lyophilized

Database Information

KEGG ID :	K14958 \| Matching products
UniProt ID :	Q8IVT5 \| Matching products
Gene ID :	GeneID 8844 \| Matching products

Handling & Safety

Storage:	-20°C (protect from light & moisture)
Shipping:	+20°C (International: +20°C)

Caution
Our products are for laboratory research use only: Not for administration to humans!

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