KMO (human), recombinant protein

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ABS-PP-20204-L.20	20 µg		-	-	10 - 15 business days*		115.00€
ABS-PP-20204-L.100	100 µg		-	-	10 - 15 business days*		205.00€

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Protein function: Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form... more

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Product information "KMO (human), recombinant protein"

Protein function: Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn) (PubMed:29429898, PubMed:23575632, PubMed:26752518, PubMed:28604669, PubMed:29208702). Required for synthesis of quinolinic acid, a neurotoxic NMDA receptor antagonist and potential endogenous inhibitor of NMDA receptor signaling in axonal targeting, synaptogenesis and apoptosis during brain development. Quinolinic acid may also affect NMDA receptor signaling in pancreatic beta cells, osteoblasts, myocardial cells, and the gastrointestinal tract (Probable). [The UniProt Consortium]

Keywords:	Kynurenine 3-hydroxylase, Kynurenine 3-monooxygenase
Supplier:	Absea
Supplier-Nr:	PP-20204-L

Properties

Conjugate:	No
Host:	E.coli
Species reactivity:	human
MW:	11.5 kD
Purity:	>85%
Format:	Lyophilized

Database Information

KEGG ID :	K00486 \| Matching products
UniProt ID :	O15229 \| Matching products
Gene ID :	GeneID 8564 \| Matching products

Handling & Safety

Storage:	-20°C (protect from light & moisture)
Shipping:	+20°C (International: +20°C)

Caution
Our products are for laboratory research use only: Not for administration to humans!

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