KDM2B (human), recombinant protein

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ABS-PP-2520-L.20	20 µg	-	-	-	Request delivery time estimate		115.00€
ABS-PP-2520-L.100	100 µg	-	-	-	Request delivery time estimate		205.00€

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Protein function: Histone demethylase that demethylates 'Lys-4' and 'Lys-36' of histone H3,... more

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Product information "KDM2B (human), recombinant protein"

Protein function: Histone demethylase that demethylates 'Lys-4' and 'Lys-36' of histone H3, thereby playing a central role in histone code (PubMed:16362057, PubMed:17994099, PubMed:26237645). Preferentially demethylates trimethylated H3 'Lys-4' and dimethylated H3 'Lys-36' residue while it has weak or no activity for mono- and tri-methylated H3 'Lys-36' (PubMed:16362057, PubMed:17994099, PubMed:26237645). Preferentially binds the transcribed region of ribosomal RNA and represses the transcription of ribosomal RNA genes which inhibits cell growth and proliferation (PubMed:16362057, PubMed:17994099). May also serve as a substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex (Probable). [The UniProt Consortium]

Keywords:	Lysine-specific demethylase 2B, CXXC-type zinc finger protein 2, F-box and leucine-rich repeat protein 10, F-box protein FBL10, F-box/LRR-repeat protein 10, JmjC domain-containing histone demethylation protein 1B, Jumonji domain-containing EMSY-interactor
Supplier:	Absea
Supplier-Nr:	PP-2520-L

Properties

Conjugate:	No
Host:	E.coli
Species reactivity:	human
MW:	22.5 kD
Format:	Lyophilized

Database Information

KEGG ID :	K10276 \| Matching products
UniProt ID :	Q8NHM5 \| Matching products
Gene ID :	GeneID 84678 \| Matching products

Handling & Safety

Storage:	-20°C (protect from light & moisture)
Shipping:	+20°C (International: +20°C)

Caution
Our products are for laboratory research use only: Not for administration to humans!

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