KCNMB3 (human), recombinant protein

KCNMB3 (human), recombinant protein
Item number Size Datasheet Manual SDS Delivery time Quantity Price
ABS-PQ-563-L.20 20 µg - -

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295.00€
ABS-PQ-563-L.100 100 µg - -

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565.00€
 
Protein function: Regulatory subunit of the calcium activated potassium KCNMA1 (maxiK) channel.... more
Product information "KCNMB3 (human), recombinant protein"
Protein function: Regulatory subunit of the calcium activated potassium KCNMA1 (maxiK) channel. Modulates the calcium sensitivity and gating kinetics of KCNMA1, thereby contributing to KCNMA1 channel diversity. Alters the functional properties of the current expressed by the KCNMA1 channel. Isoform 2, isoform 3 and isoform 4 partially inactivate the current of KCNBMA. Isoform 4 induces a fast and incomplete inactivation of KCNMA1 channel that is detectable only at large depolarizations. In contrast, isoform 1 does not induce detectable inactivation of KCNMA1. Two or more subunits of KCNMB3 are required to block the KCNMA1 tetramer. [The UniProt Consortium]
Keywords: Calcium-activated potassium channel subunit beta-3, BK channel subunit beta-3, BKbeta3, Hbeta3, Calcium-activated potassium channel, subfamily M subunit beta-3, Charybdotoxin receptor subunit beta-3, K(VCA)beta-3, Maxi K channel subunit beta-3, Slo-beta-3
Supplier: Absea
Supplier-Nr: PQ-563-L

Properties

Conjugate: No
Host: human cells
Species reactivity: human
MW: 42.5 kD
Format: Lyophilized

Handling & Safety

Storage: -20°C (protect from light & moisture)
Shipping: +20°C (International: +20°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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