Interleukin-1 receptor-like 2 (Il1rl2), partial, mouse, recombinant

Organism: Mus musculus (Mouse). Source: E.coli. Expression Region: 22-338aa. Protein Length: Partial. Tag Info: N-terminal 6xHis-SUMO-tagged. Target Protein Sequence: DTCEDIFMHN VIISEGQPFP FNCTYPPETN GAVNLTWYKT PSKSPVSNNR HLRVHQDQTW ILFLPLTLED SGIYQCVIRN AHNCYQIAVN LTVLKNHWCD SSMEGSPVNS PDVYQQILPI GKSGSLNCHL YFPESCALDS IKWYKGCEEI KAGKKYSPSG AKLLVNNVAV EDGGSYACSA RLTHLGRHFT IRNYIAVNTK EVEYGRRIPN ITYPKNNSIE VPLGSTLIVN CNITDTKENT NLRCWRVNNT LVDDYYKDSK RIQEGIETNV SLRDQIRYTV NITFLKVKME DYGRPFTCHA GVSAAYIILI YPVPDFR. Purity: Greater than 90% as determined by SDS-PAGE. Endotoxin: n/a. Biological Activity: n/a. Form: Liquid or Lyophilized powder. Buffer: If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0. Reconstitution: We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20 °C/-80 °C. Our default final concentration of glycerol is 50%. Customers could use it as reference. Storage: The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20 °C/-80 °C. The shelf life of lyophilized form is 12 months at -20 °C/-80 °C. Notes: Repeated freezing and thawing is not recommended. Store working aliquots at 4 °C for up to one week. Relevance: Receptor for interleukin-36 (IL36A, IL36B and IL36G). After binding to interleukin-36 associates with the coreceptor IL1RAP to form the interleukin-36 receptor complex which mediates interleukin-36-dependent activation of NF-kappa-B, MAPK and other pathways. The IL-36 signaling system is thought to be present in epithelial barriers and to take part in local inflammatory response, it is similar to the IL-1 system. Seems to be involved in skin inflammatory response by induction of the IL-23/IL-17/IL-22 pathway. Reference: n/a. Function: nan