IL17RD (human), recombinant protein

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ABS-PQ-595.20	20 µg		-	-	Request delivery time estimate		270.00€
ABS-PQ-595.100	100 µg		-	-	Request delivery time estimate		540.00€

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Protein function: Feedback inhibitor of fibroblast growth factor mediated Ras- MAPK signaling and... more

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Product information "IL17RD (human), recombinant protein"

Protein function: Feedback inhibitor of fibroblast growth factor mediated Ras- MAPK signaling and ERK activation (PubMed:12958313, PubMed:12807873). Regulates the nuclear ERK signaling pathway by spatially blocking nuclear translocation of activated ERK without inhibiting cytoplasmic phosphorylation of ERK (PubMed:15239952). Mediates JNK activation and may be involved in apoptosis. May inhibit FGF-induced FGFR1 tyrosine phosphorylation. Might have a role in the early stages of fate specification of GnRH-secreting neurons. Inhibits TGFB-induced epithelial-to-mesenchymal transition in lens epithelial cells. [The UniProt Consortium]

Keywords:	Interleukin-17 receptor D, IL-17 receptor D, IL-17RD, IL17Rhom, Interleukin-17 receptor-like protein, Sef homolog, hSef, Recombinant Human IL17RD Protein
Supplier:	Absea
Supplier-Nr:	PQ-595

Properties

Conjugate:	No
Host:	human cells
Species reactivity:	human
MW:	33 kD
Format:	Solution

Database Information

KEGG ID :	K05167 \| Matching products
UniProt ID :	Q8NFM7 \| Matching products
Gene ID :	GeneID 54756 \| Matching products

Handling & Safety

Storage:	-20°C (avoid repeat freezing and thawing cycles)
Shipping:	-20°C (International: -20°C)

Caution
Our products are for laboratory research use only: Not for administration to humans!

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