IL-4R alpha Protein, Mouse, Recombinant (hFc)

IL-4R alpha Protein, Mouse, Recombinant (hFc)
Item number Size Datasheet Manual SDS Delivery time Quantity Price
TGM-TMPJ-00387-5ug 5 µg - - -

7 - 10 business days*

44.00€
TGM-TMPJ-00387-20ug 20 µg - - -

7 - 10 business days*

103.00€
TGM-TMPJ-00387-100ug 100 µg - - -

7 - 10 business days*

300.00€
TGM-TMPJ-00387-200ug 200 µg - - -

7 - 10 business days*

494.00€
 
Description: Interleukin-4 receptor subunit alpha(IL-4RA), alos known as Soluble IL-4 receptor... more
Product information "IL-4R alpha Protein, Mouse, Recombinant (hFc)"
Description: Interleukin-4 receptor subunit alpha(IL-4RA), alos known as Soluble IL-4 receptor subunit alpha, belongs to the type I cytokine receptor family and type 4 subfamily. It expressed in both Th1 and Th2 cells. It functions as receptor for both interleukin 4 and interleukin 13 and couples to the JAK1/2/3-STAT6 pathway. The IL4 response is involved in promoting Th2 differentiation. The IL4/IL13 responses are involved in regulating IgE production and chemokine and mucus production at sites of allergic inflammation. In certain cell types, IL-4RA can signal through activation of insulin receptor substrates, IRS1/IRS2. The functional IL4 receptor is formed by initial binding of IL4 to IL4R. Subsequently it recruits to the complex of the common gamma chain. In immune cells, IL-4RA creates a type I receptor. In non-immune cells, it forms a type II receptor with of IL13RA1. IL4R can also interact with the IL13/IL13RA1 complex to form a similar type II receptor and interacts with the SH2-containing phosphatases, PTPN6/SHIP1, PTPN11/SHIP2 and INPP5D/SHIP.
Keywords: Soluble IL-4R-alpha , Interleukin-4 receptor subunit alpha , Soluble IL-4R-alpha , CD124 , IL-4R-alpha , IL-4R-alpha , Interleukin-4 receptor subunit alpha , IL4-BP
Supplier: TargetMol
Supplier-Nr: TMPJ-00387

Properties

Conjugate: No
MW: 80 kD

Handling & Safety

Storage: +4°C
Shipping: +20°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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