IL-1R2/CD121b Protein (recombinant human)

IL-1R2/CD121b Protein (recombinant human)
Item number Size Datasheet Manual SDS Delivery time Quantity Price
G-RPCB0941.10 10 µg - - -

10 - 15 business days*

113.00€
 
Endotoxin level: < 0.1 EU/µg of the protein by LAL method. Protein function: Non-signaling... more
Product information "IL-1R2/CD121b Protein (recombinant human)"
Endotoxin level: < 0.1 EU/µg of the protein by LAL method. Protein function: Non-signaling receptor for IL1A, IL1B and IL1RN. Reduces IL1B activities. Serves as a decoy receptor by competetive binding to IL1B and preventing its binding to IL1R1. Also modulates cellular response through non-signaling association with IL1RAP after binding to IL1B. IL1R2 (membrane and secreted forms) preferentially binds IL1B and poorly IL1A and IL1RN. The secreted IL1R2 recruits secreted IL1RAP with high affinity, this complex formation may be the dominant mechanism for neutralization of IL1B by secreted/soluble receptors. [The UniProt Consortium]
Keywords: IL1R2, IL1RB
Supplier: Assay Genie
Supplier-Nr: RPCB0941

Properties

Conjugate: No
Host: Human cells
Species reactivity: human
Purity: >95% (SDS-PAGE)

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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