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| Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
|---|---|---|---|---|---|---|---|
| G-RPCB1803.100 | 100 µg | - | - | - |
9 - 20 business days* |
774.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Endotoxin level: <1EU/µg. Protein function: Mediates the transport of phosphorylated lysosomal... more
Product information "IGF2R/CD222 Protein (recombinant human)"
Endotoxin level: <1EU/µg. Protein function: Mediates the transport of phosphorylated lysosomal enzymes from the Golgi complex and the cell surface to lysosomes (PubMed:2963003, PubMed:18817523). Lysosomal enzymes bearing phosphomannosyl residues bind specifically to mannose-6-phosphate receptors in the Golgi apparatus and the resulting receptor-ligand complex is transported to an acidic prelysosomal compartment where the low pH mediates the dissociation of the complex (PubMed:2963003, PubMed:18817523). The receptor is then recycled back to the Golgi for another round of trafficking through its binding to the retromer (PubMed:18817523). This receptor also binds IGF2 (PubMed:18046459). Acts as a positive regulator of T-cell coactivation by binding DPP4 (PubMed:10900005). [The UniProt Consortium]
| Keywords: | MPRI, M6PR, IGF2R, CD222, CI-MPR, MPR 300, M6P/IGF2R, IGF-II receptor, M6P/IGF2 receptor, CI Man-6-P receptor, 300 kDa mannose 6-phosphate receptor, Insulin-like growth factor 2 receptor, Insulin-like growth factor II receptor |
| Supplier: | Assay Genie |
| Supplier-Nr: | RPCB1803 |
Properties
| Conjugate: | No |
| Host: | Human cells |
| Species reactivity: | human |
| Purity: | >95% (HPLC) |
Database Information
| KEGG ID : | K06564 | Matching products |
| UniProt ID : | P11717 | Matching products |
| Gene ID : | GeneID 3482 | Matching products |
Handling & Safety
| Storage: | -20°C |
| Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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