IDH1, His, Human

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
GSC-Z05396-100	100 µg		-		Request delivery time estimate		457.00€
GSC-Z05396-500	500 µg		-		Request delivery time estimate		1,505.00€

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Isocitrate dehydrogenase (IDH) is a metabolic enzyme that converts isocitrate to... more

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Product information "IDH1, His, Human"

Isocitrate dehydrogenase (IDH) is a metabolic enzyme that converts isocitrate to alpha-ketoglutarate (alpha-KG). Genetic gain-of-function mutations in IDH1 and IDH2 confer a neomorphic activity that allow reduction of alpha -KG to (R)-2- hydroxyglutarate, the accumulation of which results in the development of cancers like low grade gliomas and leukemia.Isocitrate dehydrogenase 1 (IDH1) is the most frequently mutated metabolic gene in cancer.

Keywords:	IDPc, IDH1, NADP(+)-specific ICDH, Oxalosuccinate decarboxylase, Cytosolic NADP-isocitrate dehydrogenase, Isocitrate dehydrogenase [NADP] cytoplasmic
Supplier:	GenScript
Supplier-Nr:	Z05396

Properties

Conjugate:	No
Species reactivity:	human
MW:	47.35 kD
Purity:	>95% (Bis-Tris PAGE)

Database Information

KEGG ID :	K00031 \| Matching products
UniProt ID :	O75874 \| Matching products
Gene ID :	GeneID 3417 \| Matching products

Handling & Safety

Storage:	-20°C
Shipping:	-20°C (International: °C)

Caution
Our products are for laboratory research use only: Not for administration to humans!

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