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| Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
|---|---|---|---|---|---|---|---|
| G-HDFP017.10 | 10 µg | - | - |
9 - 20 business days* |
1,693.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Protein function: Part of TspanC8 subgroup, composed of 6 members that interact with the... more
Product information "Human TSPAN33 Full-Length Bioactive Membrane Protein"
Protein function: Part of TspanC8 subgroup, composed of 6 members that interact with the transmembrane metalloprotease ADAM10. This interaction is required for ADAM10 exit from the endoplasmic reticulum and for enzymatic maturation and trafficking to the cell surface as well as substrate specificity. Different TspanC8/ADAM10 complexes have distinct substrates (PubMed:26686862, PubMed:30463011, PubMed:37516108). Plays an important role in normal erythropoiesis. It has a role in the differentiation of erythroid progenitors. Negatively regulates ligand-induced Notch activity probably by regulating ADAM10 activity (PubMed:26686862). Mediates docking of ADAM10 to zonula adherens by interacting with ADAM10 and, in a PDZD11- dependent manner, with the zonula adherens protein PLEKHA7 (PubMed:30463011). [The UniProt Consortium]
| Keywords: | PEN, hPen, Penumbra, Tspan-33, Tetraspanin-33, Proerythroblast new membrane |
| Supplier: | Assay Genie |
| Supplier-Nr: | HDFP017 |
Properties
| Conjugate: | No |
| Host: | Human cells |
| Species reactivity: | human |
Database Information
| KEGG ID : | K17346 | Matching products |
| UniProt ID : | Q86UF1 | Matching products |
| Gene ID : | GeneID 340348 | Matching products |
Handling & Safety
| Storage: | -20°C (avoid repeat freezing and thawing cycles) |
| Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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