Human TRAIL R2/DR5/TNFRSF10B Protein

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
KT-TRL-HM4R2-100UG	100 µg		-		7 - 10 business days*		245.00€
KT-TRL-HM4R2-500UG	500 µg		-		7 - 10 business days*		813.00€

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Recombinant Human TRAIL R2/DR5/TNFRSF10B Protein is expressed from HEK293 with His tag and Avi... more

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Product information "Human TRAIL R2/DR5/TNFRSF10B Protein"

Recombinant Human TRAIL R2/DR5/TNFRSF10B Protein is expressed from HEK293 with His tag and Avi tag at the C-Terminus.It contains Ile56-Glu182. DR5, also called TRAIL R2, TRICK 2, TNFRSF10B, and MK is a type 1 TNF R superfamily, membrane protein which is a receptor for TRAIL (APO2 ligand). DR5 is a receptor for the cytotoxic ligand TNFSF10/TRAIL. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis.

Keywords:	CD262, DR5, DR5TRICK2B, Fas-like protein, KILLER/DR5, TNFRSF10B, TRAIL R2, TRAIL receptor 2, TRAILR2, TRICK2, TRICK2A, TRICKB, ZTNFR9, KILLER
Supplier:	KACTUS
Supplier-Nr:	TRL-HM4R2

Properties

Host:	Human cells
Species reactivity:	human
MW:	17.2 kD
Purity:	>95% (Tris-Bis PAGE),>95% (HPLC)
Format:	Lyophilized

Database Information

UniProt ID :	O14763 \| Matching products
Gene ID :	GeneID 8795 \| Matching products

Handling & Safety

Storage:	-80°C (avoid repeat freezing and thawing cycles)
Shipping:	+20°C (International: +20°C)

Caution
Our products are for laboratory research use only: Not for administration to humans!

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